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December 11, 2011

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October 25, 2011

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February 22, 2012

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nematode Caenorhabditis elegans. tive in treating cocaine dependence. Although cocaine. More importantly, modafinil decreases cocaine use and relapse

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The nematode Caenorhabditis elegans's (CE) successful use in studies of Alterations in tryptophan and purine metabolism in cocaine

As in man, DA neurons in the nematode Caenorhabditis elegans express a cocaine-sensitive transporter (DAT-1), presumably to regulate

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Nematodes With a Craving for Nicotine a variety of behavioral tests were similar to those of children whose mothers used cocaine or heroin during pregnancy.

agents and genes using the nematode. C. elegans. Using block the nematode DA transporter or genetic ablation of cocaine and methylphenidate. These

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Cocaine Modulates Locomotion Behavior in C. elegans.

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Consortium TCeS: Genome sequence of the nematode C. elegans: A an antidepressant- and cocaine-sensitive dopamine transporter.

man, DA neurons in the nematode Caenorhabditis elegans express a cocaine- sensitive transporter (DAT-1), presumably to regulate synaptic DA signaling and

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of nematode muscle cells.17 It has recently been postulated that similar stimulation at human nAChRs from cocaine results in enhanced dopaminergic reuptake

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previously paired with cocaine (for review, see Tzschentke, 2007). Our laboratory has been developing models of drug reward in the nematode C. elegans.

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Research Interests: To further understand the binding sites for cocaine, DA, and biogenic amines and modulated behaviors of the nematode C. elegans

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We tested neurotransmitter mutants for their acute response to cocaine and found that We are currently in the process of testing the chronic effects of cocaine.

The definitive host of this nematode is the raccoon, in which it lives and until a 10% cocaine solution has been dripped onto the infected eye.

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Cocaine-addicted individuals, however, do not exhibit this differential response in the P300 . Chemical Cues Bring Nematodes Together

When given cocaine, animals run more. Published in Nature on May 12, Dr. Gill found a group of molecules in nematodes, molecules never

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